John Kendrew

John Kendrew - Crystallographer, Timeline and Personal Life

Violet FieldHome › BritishJohn KendrewMarch 24, 1917357 views

0 based on 0 rates
John Kendrew Biography Stories 

John Kendrew's Personal Details

John Kendrew was an English biochemist and crystallographer who, along with Max Peutz, was one of the co-recipients of the 1962 Nobel Prize in Chemistry

InformationDetail
BirthdayMarch 24, 1917
Died onAugust 23, 1997
NationalityBritish
FamousTrinity College, Cambridge, Scientists, Chemists, Biochemists, Crystallographer
Universities
  • Trinity College, Cambridge
Notable Alumnis
  • Trinity College
  • Cambridge
Birth PlaceOxford, United Kingdom
GenderMale
Sun SignAries
Born inOxford, United Kingdom
Famous asBiochemist and Crystallographer
Died at Age80

John Kendrew's photo

Who is John Kendrew?

Sir John Cowdery Kendrew was an English biochemist and crystallographer who, along with Max Peutz, was one of the co-recipients of the 1962 Nobel Prize in Chemistry. The duo won the award for their studies of the structure of globular proteins. Born into an educated and cultured family in Oxford, John Kendrew graduated IN chemistry from Trinity College in the year World War II broke out. Subsequently, he spent the war years with the Royal Air Force as honorary Wing Commander. Afterwards, he joined the Cavendish Laboratory and there he began to work on hemoglobin with Max Ferdinand Perutz. Later his interest shifted to myoglobin and after years of intense research he was able to devise its complete structure, for which he later received the Nobel Prize in Chemistry. Apart from an outstanding researcher, Kendrew was also an excellent administrator and held many important positions simultaneously. While he was still graduate student, he helped to establish Medical Research Council Unit at the Cavendish Laboratory and held important positions there. Much later, he became the founder member of European Molecular Biology Organization and founded and ran its laboratory at Heidelberg. For many years, he also acted as the editor-in-chief at the Journal of Molecular Biology. He was also a thorough gentleman and was much revered by the scientific fraternity.

// Famous Scientists

Juliane Koepcke

Juliane Koepcke

Juliane Koepcke is a German-Peruvian biologist, who was the lone survivor among the 92 passengers and crew of the ill-fated LANSA Flight 508 that crashed in the Peruvian rainforest on 24 December 1971. Know more about her life in this biography.

Henry Cavendish

Henry Cavendish

Henry Cavendish was a theoretical chemist and physicist, renowned for discovery of hydrogen and calculation of the mass of earth. To know more about his childhood, profile, timeline and career read on

Konstantin Tsiolkovsky

Konstantin Tsiolkovsky

Konstantin Tsiolkovsky was a Russian rocket scientist and a pioneer of astronautics. This biography provides detailed information about his childhood, family, personal life, career, achievements, etc.

Childhood & Early Years

Sir John Cowdery Kendrew was born on 24 March 1917, in Oxford, U.K. His father, Wilford George Kendrew, was a reader in climatology in the University of Oxford. His mother, Evelyn May Graham Sandburg, was an art historian. For many years she lived in Florence, where she published works on the Italian Primitives.

In 1923, John Kendrew began his education at Dragon School, a well-known preparatory school in Oxford. He studied there until 1930. Afterwards he was sent to Clifton College, a co-educational independent school located in the port city of Bristol, for his secondary education.

At Clifton College, special emphasis was laid on science, rather than classical studies as was the norm those days. He passed out from there in 1936 and subsequently, received admission at Trinity College, Cambridge as a Major scholar.

In due course, he took the Tripos Part I in Chemistry, Physics, Mathematics and Biochemistry and became a Senior Scholar in Natural Sciences. Finally he graduated in 1939, taking Tripos Part II in Chemistry. Soon after this event, the World War II broke out and Great Britain got involved in it.

John Kendrew spent first few months of the war doing research on reaction kinetics under the supervision of Dr. E.A. Moelwyn Hughes. Subsequently, he became a member of the Air Ministry Research Establishment, which was later renamed as Telecommunications Research Establishment. Here he worked mainly on radar.

From 1940, Kendrew began working on operation research under Sir Robert Watson-Watt at the Royal Air Force Headquarters and held the honorary rank of Wing Commander. Later, he was posted in the Middle East and subsequently in the South East Asia.

While in Ceylon (now Sri Lanka), he met the John Desmond Bernal, the great structural chemist and later scientific adviser to Lord Mountbatten. Later on, as he was coming back to England after the surrender of Japan, he also met Linus Pauling at the California Institute of Technology, Pasadena.

Both these scientists were greatly interested in protein and persuaded Kendrew to switch to biology. Influenced by their knowledge and enthusiasm, Kendrew decided to start working on the structure of proteins even before he reached home.

Career

In 1946, on coming back to England, John Cowdery Kendrew approached Max Ferdinand Perutz. Perutz was a student of J. D. Bernal (whom Kendrew had met in Ceylon) and was working on structure of hemoglobin at the Cavendish Laboratory at that time.

Some time now, he also met Joseph Barcroft, an English physiologist, best known for his study on oxygenation of blood. Barcroft suggested that Kendrew might make a comparative protein crystallographic study of adult and fetal sheep hemoglobin.

Subsequently, Kendrew began his doctoral research under Perutz, who also taught him the elements of crystallography. Concurrently, they also began to work together under the direction of Sir Lawrence Bragg.

In 1947, while he was still working on his doctoral thesis Kendrew became a Fellow of Peterhouse. In the same year, he and Perutz established Medical Research Council Unit for Molecular Biology in the Cavendish Laboratory under the guidance of Sir Lawrence Bragg. Subsequently, Kendrew became its Deputy Director and held the position till 1975.

Meanwhile, Kendrew and Perutz continued their work on the structure of sheep hemoglobin. Later, when the resources became scarce, Kendrew began to work on myoglobin, an iron and oxygen binding protein found in the muscle tissue of vertebrates. It is closely related to hemoglobin, but is much smaller in size.

In 1949, Kendrew received his PhD degree. However, he carried on his work on structure of myoglobin because he was yet to determine its crystalline arrangement. Initially, he faced a lot of problems in that.

In 1953, Perutz discovered a new technique called ‘multiple isomorphic replacements’ that was capable of solving the phase problem. Kendrew applied this technique to the simpler molecule myoglobin.

Before Kendrew could succeed in this project, he and Perutz moved with Bragg to Royal Institution in London. In 1954, both of them were appointed as the Honorary Readers of the Davy Faraday Research Laboratory at the Royal Institution. They held their respective posts till 1968.

Meanwhile, they continued with their research work. In 1957, after taking thousands of photographs and measurements, Kendrew was able to unravel the structure of protein myoglobin. However, the pictures were still very blurred and therefore Kendrew kept on working on them.

By 1959, after many more photographs and measurements, Kendrew was able to achieve a very high resolution. Most of the atoms in the myoglobin molecule were now clearly visible. He worked further on it and was able to determine the location of each atom in the molecule very soon.

Shortly, Perutz, who had been working on hemoglobin, was also able to describe its structure. More importantly, it was found that the helical chains that Kendrew found in myoglobin were also present hemoglobin. This stimulated activity in molecular biology all over the world.

From the beginning of 1960s, Kendrew became more interested in policy matters than in direct research. In 1963, he started working for the establishment of the European Molecular Biology Organization; becoming its founder member when the organization was launched in July 1964.

In 1974, he successfully persuaded governments of different European countries to establish a European Molecular Biology Laboratory in Heidelberg. He became its first director, holding the post till 1981.

In 1981, after his retirement from the European Molecular Biology Laboratory, Kendrew became President of St John's College at Oxford University, a post he held till 1987. Subsequently, he returned to Cambridge, where he was made an Honorary Fellow of both Trinity College and Peterhouse.

Major Works

Kendrew is best remembered for his work on myoglobin. Since it is found in the muscle tissue of vertebrates he first started working with horse heart, but later found that muscles from diving animals would be more suitable. Therefore he procured whale meat from Peru and started working with it.

In 1957, using multiple isomorphic replacements technique and x-ray analysis, he was able to develop a three-dimensional model of the myoglobin molecule with 6A resolution. Not satisfied with the result, he continued with the work and in 1959, he was able to devise a more complete structure and show the arrangement of the amino acid units in it.

Awards & Achievements

In 1962, Kendrew and Perutz jointly received the Nobel Prize in Chemistry "for their studies of the structures of globular proteins".

In 1965, he was awarded the Royal Medal by the Royal Society "in recognition of his distinguished contributions to the complete structural analysis of a protein molecule (myoglobin), particularly the biological aspects of this study."

In 1974, Kendrew was made a Companion of the British Empire.

In 1967, he became Fellow of the American Society of Biological Chemists and also an Honorary Member of the International Academy of Science.

Personal Life & Legacy

Kendrew was a life-long bachelor. He was also a very shy and private person with high artistic taste. Music, history of art and travelling through Italy were among his hobbies.

After his retirement from St John's College at Oxford University, he returned to live in Cambridge. Here, he died on 26 August 1997, at the age of 80.

On 16 October 2010, the University of Oxford opened the Kendrew Quadrangle at St John's College in Oxford in his honor.

Trivia

The answering message on Kendrew’s phone was, "Please be patient and I shall get back to you as soon as possible".

// Famous Chemists

Henry Cavendish

Henry Cavendish

Henry Cavendish was a theoretical chemist and physicist, renowned for discovery of hydrogen and calculation of the mass of earth. To know more about his childhood, profile, timeline and career read on

Walter Kohn

Walter Kohn

Nobel Laureate Walter Kohn was an Austrian-born American theoretical chemist and physicist. Check out this biography to know about his childhood, life, achievements, works & timeline.

Jabir Ibn Hayyan

Jabir Ibn Hayyan

Jabir Ibn Hayyan was a medieval era polymath. Check out this biography to know about his life, works and achievements.

John Kendrew's awards

YearNameAward

Other

01962 - Nobel Prize in Chemistry
0 1965 - Royal Medal
0 1988 - William Procter Prize for Scientific Achievement

John Kendrew biography timelines

  • // 24th Mar 1917
    Sir John Cowdery Kendrew was born on 24 March 1917, in Oxford, U.K. His father, Wilford George Kendrew, was a reader in climatology in the University of Oxford. His mother, Evelyn May Graham Sandburg, was an art historian. For many years she lived in Florence, where she published works on the Italian Primitives.
  • // 1923 To 1930
    In 1923, John Kendrew began his education at Dragon School, a well-known preparatory school in Oxford. He studied there until 1930. Afterwards he was sent to Clifton College, a co-educational independent school located in the port city of Bristol, for his secondary education.
  • // 1936
    At Clifton College, special emphasis was laid on science, rather than classical studies as was the norm those days. He passed out from there in 1936 and subsequently, received admission at Trinity College, Cambridge as a Major scholar.
  • // 1939
    In due course, he took the Tripos Part I in Chemistry, Physics, Mathematics and Biochemistry and became a Senior Scholar in Natural Sciences. Finally he graduated in 1939, taking Tripos Part II in Chemistry. Soon after this event, the World War II broke out and Great Britain got involved in it.
  • // 1940
    From 1940, Kendrew began working on operation research under Sir Robert Watson-Watt at the Royal Air Force Headquarters and held the honorary rank of Wing Commander. Later, he was posted in the Middle East and subsequently in the South East Asia.
  • // 1946
    In 1946, on coming back to England, John Cowdery Kendrew approached Max Ferdinand Perutz. Perutz was a student of J. D. Bernal (whom Kendrew had met in Ceylon) and was working on structure of hemoglobin at the Cavendish Laboratory at that time.
  • // 1947 To 1975
    In 1947, while he was still working on his doctoral thesis Kendrew became a Fellow of Peterhouse. In the same year, he and Perutz established Medical Research Council Unit for Molecular Biology in the Cavendish Laboratory under the guidance of Sir Lawrence Bragg. Subsequently, Kendrew became its Deputy Director and held the position till 1975.
  • // 1949
    In 1949, Kendrew received his PhD degree. However, he carried on his work on structure of myoglobin because he was yet to determine its crystalline arrangement. Initially, he faced a lot of problems in that.
  • // 1953
    In 1953, Perutz discovered a new technique called ‘multiple isomorphic replacements’ that was capable of solving the phase problem. Kendrew applied this technique to the simpler molecule myoglobin.
  • // 1954 To 1968
    Before Kendrew could succeed in this project, he and Perutz moved with Bragg to Royal Institution in London. In 1954, both of them were appointed as the Honorary Readers of the Davy Faraday Research Laboratory at the Royal Institution. They held their respective posts till 1968.
  • // 1957
    Meanwhile, they continued with their research work. In 1957, after taking thousands of photographs and measurements, Kendrew was able to unravel the structure of protein myoglobin. However, the pictures were still very blurred and therefore Kendrew kept on working on them.
  • // 1957 To 1959
    In 1957, using multiple isomorphic replacements technique and x-ray analysis, he was able to develop a three-dimensional model of the myoglobin molecule with 6A resolution. Not satisfied with the result, he continued with the work and in 1959, he was able to devise a more complete structure and show the arrangement of the amino acid units in it.
  • // 1959
    By 1959, after many more photographs and measurements, Kendrew was able to achieve a very high resolution. Most of the atoms in the myoglobin molecule were now clearly visible. He worked further on it and was able to determine the location of each atom in the molecule very soon.
  • // 1962
    In 1962, Kendrew and Perutz jointly received the Nobel Prize in Chemistry "for their studies of the structures of globular proteins".
  • // 1963 To Jul 1964
    From the beginning of 1960s, Kendrew became more interested in policy matters than in direct research. In 1963, he started working for the establishment of the European Molecular Biology Organization; becoming its founder member when the organization was launched in July 1964.
  • // 1965
    In 1965, he was awarded the Royal Medal by the Royal Society "in recognition of his distinguished contributions to the complete structural analysis of a protein molecule (myoglobin), particularly the biological aspects of this study."
  • // 1967
    In 1967, he became Fellow of the American Society of Biological Chemists and also an Honorary Member of the International Academy of Science.
  • // 1974 To 1981
    In 1974, he successfully persuaded governments of different European countries to establish a European Molecular Biology Laboratory in Heidelberg. He became its first director, holding the post till 1981.
  • // 1974
    In 1974, Kendrew was made a Companion of the British Empire.
  • // 1981 To 1987
    In 1981, after his retirement from the European Molecular Biology Laboratory, Kendrew became President of St John's College at Oxford University, a post he held till 1987. Subsequently, he returned to Cambridge, where he was made an Honorary Fellow of both Trinity College and Peterhouse.
  • // 26th Aug 1997
    After his retirement from St John's College at Oxford University, he returned to live in Cambridge. Here, he died on 26 August 1997, at the age of 80.

// Famous Trinity College, Cambridge

Isaac Newton

Isaac Newton

Isaac Newton was an English scientist and mathematician, who discovered gravitation and Newtonian Mechanics. Read this biography to find more on his life.

Aleister Crowley

Aleister Crowley

Aleister Crowley was an occultist and ceremonial magician who founded the ethical philosophy of Thelema. This biography of Aleister Crowley provides detailed information about his childhood, life, achievements, works & timeline.

William Makepeace Thackeray

William Makepeace Thackeray

William Thackeray was an English novelist and satirist. Read this brief biography to find more on his life & timeline.

Srinivasa Ramanujan

Srinivasa Ramanujan

Srinivasa Ramanujan was an Indian mathematician who made significant contributions to mathematical analysis, number theory, and continued fractions. Check out this biography to know about his childhood, life, achievements, works & timeline. .

Jared Diamond

Jared Diamond

Jared Mason Diamond is an American scientist and author reputed for his highly acclaimed and popular science books.

J. J. Thomson

J. J. Thomson

J.J. Thomson was an English physicist and mathematician. This biography profiles his childhood, life, academic career, research and timeline.

John Kendrew's FAQ

  • What is John Kendrew birthday?

    John Kendrew was born at 1917-03-24

  • When was John Kendrew died?

    John Kendrew was died at 1997-08-23

  • Which age was John Kendrew died?

    John Kendrew was died at age 80

  • Where is John Kendrew's birth place?

    John Kendrew was born in Oxford, United Kingdom

  • What is John Kendrew nationalities?

    John Kendrew's nationalities is British

  • What was John Kendrew universities?

    John Kendrew studied at Trinity College, Cambridge

  • What was John Kendrew notable alumnis?

    John Kendrew's notable alumnis is Trinity College, Cambridge

  • What is John Kendrew's sun sign?

    John Kendrew is Aries

  • How famous is John Kendrew?

    John Kendrew is famouse as Biochemist and Crystallographer