Robert Huber

Huber married Christa Essig in 1960. The couple was blessed with four children, two daughters and two sons. However, Huber and Christa parted ways.

Currently, Huber is married to Brigitte Doleshel.

Robert Huber was born on February 20, 1937 in Munich, to Sebastian and Helene Huber. His father was a bank cashier. Robert had a younger sister.

Young Huber gained his early education from Humanistisches Karls-Gymnasium from 1947 to 1956. His fascination for chemistry began since then as he read all books on chemistry he could lay his hands on. Later, Huber studied chemistry at the Technische Hochschule, receiving his diploma in 1960.

Upon receiving his diploma, Huber involved himself in research, using crystallography to elucidate the structure of organic compounds. The research work gained him a stipend from the Bayerisches Ministerium für Erziehung und Kultur and later from the Studienstiftung des Deutschen Volkes that took care of his financial problems.

Huber went on to study crystallography under W. Hoppe at the Munich Technical University from where he gained a doctorate degree in 1963; his thesis work was on the crystal structure of a diazo compound.

Robert Huber’s PhD on the crystal structure of a diazo compound influenced much of his future works as he became aware of the power of crystallography. He propelled his career in the same direction, researching on crystallography.

Huber carried out most of his work at Hoppe’s laboratory, working on crystallographic studies of the insect metamorphosis hormone ecdysone and at Karlson’s laboratory at the Physiologisch-Chemisches Institut der Universität München.

During his work at the Karlson’s laboratory, he found by a simple crystallographic experiment the molecular weight and probable steroid nature of ecdysone. This discovery led Huber to continue his research in the field of crystallography.

After a number of structure determinations of organic compounds and methodical development of Patterson search techniques, with the support of Hoppe and Braunitzer, Huber began his crystallographic work on the insect protein erythrocruorin (with Formanek) in 1967.

In 1970, Huber began work on the basic pancreatic trypsin inhibitor. It eventually became the model compound for the development of protein NMR, molecular dynamics, and experimental folding studies in other laboratories.

The magnum opus of Huber’s career came in 1980s when he, along with Johann Deisehofer and Hartmut Michel, determined the three dimensional structure of a photosynthesis reaction centre. An internationally recognized expert in the use of X-ray diffraction, Huber determined the atomic structure of complex molecules such as proteins by analysing the manner in which the crystal’s atoms scatter a beam of X rays. Along with his colleagues he used the same technique to determine the structure of a protein complex which is essential to photosynthesis in certain bacteria.