Henry Gray

In 1861, Henry Gray was engaged to be married. Unfortunately, he died before the marriage could take place.

Sometime in 1861, Henry’s ten year old nephew, Charles Gray, was inflicted with small pox, a dreaded disease in those days. Henry nursed him day and night. Although Charles recovered, Henry was afflicted with the severest form of small pox.

It is said that the lesions were so numerous one could not distinguish one from another. He died from the disease on June 13, 1861 and buried at East Highgate Cemetery in London. He was only 34 years old at the time of his death.

Henry Gray was born in Belgravia, London, in 1827. His father, whose name is not known, was private messenger to King George IV and upon his death to his successor King William IV. Nothing is known about his mother. Henry was one of their four children.

Two of his siblings, a sister and a brother, died young. His surviving brother, Thomas William Gray, had two daughters, one of whom left some basic details about his background. He also had a nephew called Charles Gray, who was probably the son of his deceased brother.

The earliest record that we have is that he entered St. George’s Hospital on 6 May 1845 as a medical student. An article published in the St. George’s Hospital Gazette of 21 May 1908, provides a rudimentary picture of his college years.

Those who had known Gray during those days described him as a painstaking and methodical worker. It is also said that he learnt anatomy by dissecting each organ for himself rather than by watching others do it, as was the practice in those days.

Gray also published several papers while he was still a student. ‘The Origin, Connexions and Distribution of Nerves to the Human Eye and Its Appendages, Illustrated by Comparative Dissections of the Eye in Other Vertebrate Animals’, published in 1848, was one of them.

In 1852, after finishing his stint as house surgeon at the St. George’s Hospital, Gray was appointed a demonstrator of anatomy at the same hospital. In the same year, he published two major papers in the ‘Philosophical Transactions’, a science journal published by Royal Society.

The first article titled, ‘On the Development of the Retina and Optic Nerve, and of the Membranous Labyrinth and Auditory Nerve', was based on his work on chick embryo. In it, he demonstrated that the retina develops from a protrusion of the brain.

His second article, ‘On the Development of the Ductless Glands in the Chick’, dealt with the adrenal glands, thyroids, and the spleen. These works impressed the scholars so much that in the same year, he was appointed a Fellow of the Royal Society. He was only 25 years old at that time.

In 1853, Gray was made a lecturer of anatomy. With the support of a grant from Royal Society, he now continued his work on spleen, performing chemical as well as ligaturing experiments on its blood.

The experimentation culminated into one of the major works of his life; a treatise titled ‘The Structure and Use of the Spleen’. Published in 1854, it not only contains his own observations, but also a review of the previous works on spleen.

Henry Gray is best remembered for his book, ‘Anatomy: Descriptive and Surgical.’ In spite of the fact that there were other books readily available on anatomy, it became an instant hit as much for its lucid language and logical arrangement of topics as for the 363 illustrations made by Carter.

The book was first published in Great Britain in 1858 and in the United States of America in 1859. Thereafter, Gray once again revised the text and the second edition was published in 1860.

After his death, the book continued to be revised and republished as ‘Gray’s Anatomy’ and the latest (the 41st) edition of the book was published in September 2015. Even today, it is widely regarded as the most important work on anatomy.

‘The Structure and Use of the Spleen’ is another of his important works. In it, he established the origin of the spleen from the dorsal mesogastrium, a discovery mistakenly attributed to Johannes Müller and also provided description of the lymphatics, the nerves and the circulation in the spleen.